Vishwa-Syntharo

Pharmaceutical Chemicals

Vishwa-Syntharo is a Joint Venture between Vishwa Pharma Nexus Corporation, India, and Syntharo Fine Chemicals, Germany for providing products and services to Pharmaceutical Chemicals Industry and Speciality/Fine Chemical industry.

SERVICES

  • Custom Synthesis (Fine/Specialty Chemicals/API’s)
  • Custom Manufacturing (API’s, Fine & Specialty Chemicals, Pharmaceutical Chemicals)
  • Process Development (Fine/Specialty Chemicals/API’s)
  • Chemistry for drug discovery
  • Scale-up of technologies
  • Analytical Services
Pharmaceutical Chemicals
Custom SynthesisDevelop process Scale-up to make required quantity of chemical (grams to multiple kilos)
Process DevelopmentRoute selection Research & Development Optimization of process Processes can be used in-house or licensed to the location required by the customer
Chemistry for Drug DiscoveryChemistry services for Lead optimization Modification of synthesis route Providing material for trials
Analytical servicesAnalytical method development Synthesis and characterization of hard-to-get impurity standards
Scale-up of TechnologiesIn-licensing of laboratory-scale processes, fine-tuning them and scaling up to make larger quantities as required
Custom manufacturingMulti-kilo to multi-metric ton manufacturing of pharmaceutical and specialty / fine chemicals

KEY CAPABILITIES

Pharmaceutical Chemicals

Asymmetric Synthesis

  •    Chiral alkylation
  •    Asymmetric Dihydroxylation,
  •    Sharpless, Heck Epoxidation

Oxidation

  •    Classical (Jones, KMnO4, CrO3, MnO2 etc)
  •    Swern
  •    Moffat
  •    Corey-Kim
  •    Transition Metal Catalyzed

Reduction

  •    Metal Hydrides
  •    Homogeneous & Heterogeneous catalysed
  •    Transfer Hydrogenation
  •    Dissolving Metal Reduction

Others

  •    Fluorination (DAST on lab scale, NFSI on lab and kilo scale)
  •    Carbonylation
  •    Cyanation

Organometallic

  •    Heck arylation
  •    Suzuki coupling
  •    Sonagashira coupling

Common chemistries regularly performed are not included in the above.

Chemistries that they do not handle: Reactions involving Phosgene; HCN gas

CARBOHYDRATES

Basic monosachharides

  • Differentially protected and derivatized monosaccharides

Polysaccharides

  • Typically di- and tri-saccharides

Protected amino-sugars

  • Such as (D)-Glucosamine

Configurational inversion

  • Such as SN2-displacement or oxidation-reduction sequence) to arrive at rare sugars

Carbohydrate-derived chiral synthons

  • Performing sequential chemical transformations on the chiral-pool derived from sugars to make chiral synthons.

FLUORINE CHEMISTRY

Fluorinated chemicals

Custom synthesis of:

  • Fluorinated starting materials
  • Fluorinated intermediates
  • Fluorinated drugs

Fluorinated chemicals

  • NFSI;
  • DAST (at small scale only);
  • Selectfluor; deoxyfluor

Through association with an industry leader in fluorine chemistry they can offer fluorination at a large scale


Vishwa-Syntharo PharmaChem Private Limited
Regd. Office
32, First Main Road,
CIT Colony, Mylapore,
Chennai,
600 004
Tamil Nadu
India.
Tel : +91 44 43536710

R&D
2C, Dr. Subramania Siva Salai,
CMDA Industrial Estate,
Maraimalai Nagar,
603 209
Tamil Nadu
India.
Tel : +91 44 47431610

Email : info@vishwa-syntharo.com
Website : www.vishwa-syntharo.com

Syntharo Germany
Syntharo Fine Chemicals GmbH
Industriepark Troisdorf Geb. 38
Mülheimer Strasse 27 , 53840
Troisdorf, Germany
Tel: +49 2241 25569-0


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