Scigenics (India) Pvt. Ltd. is a company that specializes in the design and manufacture of Industrial Stirred Tank Fermenters for various applications. They offer a range of fermenters that are suitable for basic research, pilot scales, and production scales.
Lab scale in situ sterilizable stirred tank fermenters
Lab scale in situ sterilizable stirred tank fermenters are small-scale fermentation systems that are designed for use in a laboratory setting. These fermenters are used to grow microorganisms for a variety of purposes, including the production of biopharmaceuticals, food and beverages, and other products.
In situ sterilizable stirred tank fermenters are designed to be sterilized while in use, which means that they can be sterilized without being taken apart. This is a convenient feature because it allows the fermenter to be used repeatedly without the need for frequent cleaning and sterilization.
Stirred tank fermenters consist of a tank, or bioreactor, in which the fermentation process takes place. The tank is equipped with a stirrer to mix the contents and a heating or cooling system to control the temperature. Some fermenters also have additional features, such as pH and dissolved oxygen sensors, to monitor and control the fermentation process.
Lab scale in situ sterilizable stirred tank fermenters are typically used in research and development, as well as in small-scale production of biopharmaceuticals and other products. They are often used to test new fermentation processes and to optimize conditions for large-scale production.
Air Lift Fermenters Industrial Stirred Tank Fermenters
Air lift fermenters (ALFs) are a type of bioreactor used for the cultivation of microorganisms in a liquid medium. They are called “air lift” fermenters because they rely on the movement of air through the liquid medium to mix and aerate the culture.
ALFs consist of a cylindrical vessel with an internal draft tube that extends from the bottom to near the top of the vessel. Air is injected into the bottom of the draft tube, which creates a flow of air through the liquid. This flow of air lifts the liquid and creates mixing and aeration of the culture.
ALFs have several advantages over other types of bioreactors, including low energy consumption, simple design and construction, and the ability to operate at high cell densities. They are often used in the production of biopharmaceuticals, food and beverages, and other products.
ALFs can be used in a variety of applications, including batch, fed-batch, and continuous processes. They can also be used for both aerobic and anaerobic fermentation processes. In addition, ALFs can be used for the cultivation of a wide range of microorganisms, including bacteria, yeast, and fungi.
Aerobic/ Anaerobic Fermenters Industrial Stirred Tank Fermenters
Aerobic fermenters are bioreactors that are used to cultivate microorganisms in the presence of oxygen. These fermenters are typically used for the production of products such as biofuels, bioplastics, and other chemicals. Aerobic fermentation processes are characterized by the use of oxygen as the primary electron acceptor in the metabolism of the microorganisms.
On the other hand, anaerobic fermenters are bioreactors used to cultivate microorganisms in the absence of oxygen. These fermenters are typically used for the production of products such as ethanol, acetic acid, and other chemicals. Anaerobic fermentation processes are characterized by the use of an electron acceptor other than oxygen in the metabolism of the microorganisms.
Aerobic and anaerobic fermenters can be used in a variety of applications, including batch, fed-batch, and continuous processes. They can also be used for the cultivation of a wide range of microorganisms, including bacteria, yeast, and fungi.
The choice between using an aerobic or anaerobic fermenter depends on the requirements of the specific fermentation process and the microorganisms being cultivated. Factors to consider include the products being produced, the metabolic pathways of the microorganisms, and the oxygen requirements of the process.
Mammalian Cell Culture Bioreactors
Mammalian cell culture bioreactors are specialized bioreactors used for the cultivation of mammalian cells in a controlled environment. These bioreactors are used in a variety of applications, including the production of biopharmaceuticals, such as monoclonal antibodies, vaccines, and other therapeutic proteins.
Mammalian cell culture bioreactors are designed to mimic the in vivo environment of mammalian cells as closely as possible. They are equipped with various features to support the growth and proliferation of the cells, including temperature control, pH control, and dissolved oxygen control. Some bioreactors also have features for removing waste products and for adding nutrients to the culture.
Mammalian cell culture bioreactors come in a range of sizes and designs, from small benchtop systems to large production-scale bioreactors. They can be used in batch, fed-batch, and continuous processes, depending on the specific requirements of the culture.
Mammalian cell culture bioreactors are an important tool in the production of biopharmaceuticals and other products derived from mammalian cells. They allow for the cultivation of cells under controlled conditions, which can improve the yield and purity of the final product.
Plant Tissue – Callus Culture Bioreactors
Plant tissue culture bioreactors are specialized bioreactors used for the cultivation of plant cells, tissues, or organs in a controlled environment. These bioreactors are used in a variety of applications, including the production of plant-derived products, such as secondary metabolites, pharmaceuticals, and other biologically active compounds.
Plant tissue culture bioreactors are designed to mimic the in vivo environment of plant cells as closely as possible. They are equipped with various features to support the growth and proliferation of the cells, including temperature control, pH control, and dissolved oxygen control. Some bioreactors also have features for removing waste products and for adding nutrients to the culture.
Callus culture is a type of plant tissue culture that involves the cultivation of undifferentiated cells, called callus, from plant tissue. Callus culture bioreactors are used to cultivate callus in a controlled environment, allowing for the mass production of plant cells or tissues.
Plant tissue culture bioreactors come in a range of sizes and designs, from small benchtop systems to large production-scale bioreactors. They can be used in batch, fed-batch, and continuous processes, depending on the specific requirements of the culture.
Plant tissue culture bioreactors are an important tool in the production of plant-derived products and in plant research. They allow for the cultivation of plant cells under controlled conditions, which can improve the yield and purity of the final product.
Algal Photo Bioreactors Industrial Stirred Tank Fermenters
Algal photo bioreactors (also known as photobioreactors or PBRs) are specialized bioreactors used for the cultivation of algae in a controlled environment. These bioreactors are used in a variety of applications, including the production of biofuels, bioplastics, and other chemicals.
Algal photo bioreactors are designed to mimic the natural growth environment of algae, with the goal of optimizing the growth and productivity of the algae. They are equipped with various features to support the growth and proliferation of the algae, including temperature control, pH control, and dissolved oxygen control. Some bioreactors also have features for removing waste products and for adding nutrients to the culture.
One of the key features of algal photo bioreactors is the ability to provide light to the algae. Algae are photosynthetic organisms, which means they use light energy to convert carbon dioxide and water into organic matter. Algal photo bioreactors use artificial light sources, such as LED lamps or fluorescent lamps, to provide the light needed for photosynthesis.
Algal photo bioreactors come in a range of sizes and designs, from small benchtop systems to large production-scale bioreactors. They can be used in batch, fed-batch, and continuous processes, depending on the specific requirements of the culture.
Algal photo bioreactors are an important tool in the production of biofuels and other products derived from algae. They allow for the cultivation of algae under controlled conditions, which can improve the yield and productivity of the algae.
Gas Sequestration Fermenters Industrial Stirred Tank Fermenters
Gas sequestration fermenters are specialized bioreactors used for the cultivation of microorganisms that are capable of capturing and storing gases, such as carbon dioxide (CO2). These fermenters are used in a variety of applications, including the production of biofuels and the reduction of greenhouse gas emissions.
Gas sequestration fermenters are designed to provide the optimal conditions for the growth and metabolism of the microorganisms being cultivated. They are equipped with various features to support the growth and proliferation of the microorganisms, including temperature control, pH control, and dissolved oxygen control. Some fermenters also have features for removing waste products and for adding nutrients to the culture.
One of the key features of gas sequestration fermenters is the ability to control the concentration and flow of gases, such as CO2, in the culture. This is important because the microorganisms being cultivated rely on gases as a source of energy or as a substrate for metabolism.
Gas sequestration fermenters come in a range of sizes and designs, from small benchtop systems to large production-scale fermenters. They can be used in batch, fed-batch, and continuous processes, depending on the specific requirements of the culture.
Gas sequestration fermenters are an important tool in the production of biofuels and in the reduction of greenhouse gas emissions. They allow for the cultivation of microorganisms that are capable of capturing and storing gases under controlled conditions, which can improve the efficiency and effectiveness of the process.
In-Situ Sterilizable Solid State Reactors
In-situ sterilizable solid state reactors are specialized bioreactors used for the cultivation of microorganisms in a solid state medium, such as a solid substrate or a bed of particles. These reactors are designed to be sterilized while in use, which means that they can be sterilized without being taken apart. This is a convenient feature because it allows the reactor to be used repeatedly without the need for frequent cleaning and sterilization.
Solid state reactors are used in a variety of applications, including the production of biofuels, bioplastics, and other chemicals. They are often used to cultivate microorganisms that are capable of growing on a solid substrate, such as lignocellulosic materials or agricultural waste.
Solid state reactors are equipped with various features to support the growth and metabolism of the microorganisms being cultivated. They may have features for controlling temperature, pH, and dissolved oxygen, as well as for removing waste products and adding nutrients to the culture.
Solid state reactors come in a range of sizes and designs, from small benchtop systems to large production-scale reactors. They can be used in batch, fed-batch, and continuous processes, depending on the specific requirements of the culture.
In-situ sterilizable solid state reactors are an important tool in the production of biofuels and other products derived from microorganisms grown on a solid substrate. They allow for the cultivation of microorganisms under controlled conditions, which can improve the yield and productivity of the process.
In-Situ Sterilizable Mist Bioreactors for Diazotrophs Growing on Legumes
In-situ sterilizable mist bioreactors are specialized bioreactors used for the cultivation of microorganisms in a mist environment. These bioreactors are designed to be sterilized while in use, which means that they can be sterilized without being taken apart. This is a convenient feature because it allows the bioreactor to be used repeatedly without the need for frequent cleaning and sterilization.
Mist bioreactors are used in a variety of applications, including the cultivation of microorganisms that require a high humidity environment. They are often used to cultivate microorganisms that are sensitive to drying out or that require a high relative humidity for optimal growth.
Diazotrophs are a group of microorganisms that are capable of fixing nitrogen from the atmosphere into a form that plants can use as a nutrient. They are often associated with the roots of legumes, such as beans and peas, and can help improve soil fertility by providing a source of nitrogen for the plants.
In-situ sterilizable mist bioreactors may be used to cultivate diazotrophs on legumes in a controlled environment. These bioreactors can provide the high humidity environment that is required for optimal growth of the diazotrophs and may be used to study the interaction between the diazotrophs and the legume plants.
Mist bioreactors come in a range of sizes and designs, from small benchtop systems to large production-scale bioreactors. They can be used in batch, fed-batch, and continuous processes, depending on the specific requirements of the culture.
Top Driven/ Bottom Driven – Mechanically Sealed and Magnetically Sealed Agitated Vessels/Reactors/Fermenters
Agitated vessels, reactors, and fermenters are types of bioreactors used for the cultivation of microorganisms in a liquid medium. These bioreactors are equipped with an agitator, or stirrer, to mix the contents of the vessel and to provide oxygen to the microorganisms.
Top-driven agitated vessels are equipped with an agitator that is mounted on the top of the vessel. The agitator is typically driven by an electric motor or other power source, and it rotates to mix the contents of the vessel.
Bottom-driven agitated vessels are equipped with an agitator that is mounted on the bottom of the vessel. The agitator is typically driven by an electric motor or other power source, and it rotates to mix the contents of the vessel.
Mechanically sealed agitated vessels are equipped with a mechanical seal to prevent leakage from the vessel. The mechanical seal is typically located between the agitator and the vessel wall and is designed to minimize the risk of leakage.
Magnetically sealed agitated vessels are equipped with a magnetic seal to prevent leakage from the vessel. The magnetic seal is typically located between the agitator and the vessel wall and uses a magnetic field to minimize the risk of leakage.
Agitated vessels, reactors, and fermenters come in a range of sizes and designs, from small benchtop systems to large production-scale bioreactors. They can be used in batch, fed-batch, and continuous processes, depending on the specific requirements of the culture.
The choice between a top-driven or bottom-driven agitated vessel, as well as between a mechanically sealed or magnetically sealed vessel, depends on the specific requirements of the application. Factors to consider include the size and shape of the vessel, the type of microorganisms being cultivated, and the process conditions.
Industrial scale in situ sterilizable stirred tank fermenters
Industrial scale in situ sterilizable stirred tank fermenters are large-scale fermentation systems that are designed for use in an industrial setting. These fermenters are used to grow microorganisms for a variety of purposes, including the production of biopharmaceuticals, food and beverages, and other products.
In situ sterilizable stirred tank fermenters are designed to be sterilized while in use, which means that they can be sterilized without being taken apart. This is a convenient feature because it allows the fermenter to be used repeatedly without the need for frequent cleaning and sterilization.
Stirred tank fermenters consist of a tank, or bioreactor, in which the fermentation process takes place. The tank is equipped with a stirrer to mix the contents and a heating or cooling system to control the temperature. Some fermenters also have additional features, such as pH and dissolved oxygen sensors, to monitor and control the fermentation process.
Industrial scale in situ sterilizable stirred tank fermenters are used in large-scale production of biopharmaceuticals and other products. They are often used to optimize and scale up fermentation processes developed in the laboratory.
The design and operation of industrial scale in situ sterilizable stirred tank fermenters are similar to those of lab scale fermenters, but they are much larger in size and capacity. They may also have additional features and controls to support the larger scale of production.
Upstream and Downstream GMP Vessels
In the context of biopharmaceutical production, “upstream” processes refer to the activities that take place before the fermentation or cell culture process, while “downstream” processes refer to the activities that take place after the fermentation or cell culture process.
Upstream GMP vessels are bioreactors and other types of equipment used in the upstream processes of biopharmaceutical production. These vessels are designed and constructed to meet the regulatory requirements for the production of biopharmaceuticals and other regulated products.
Upstream GMP vessels may be used for a variety of purposes, including the cultivation of microorganisms or cells, the preparation of media and other nutrients, and the sterilization of equipment and materials.
Downstream GMP vessels are bioreactors and other types of equipment used in the downstream processes of biopharmaceutical production. These vessels are designed and constructed to meet the regulatory requirements for the production of biopharmaceuticals and other regulated products.
Downstream GMP vessels may be used for a variety of purposes, including the separation and purification of the product, the formulation and filling of the product into final containers, and the testing and quality control of the product.
Both upstream and downstream GMP vessels are important tools in the production of biopharmaceuticals and other regulated products. They are designed and constructed to meet the regulatory requirements for quality, purity, and safety, and they allow for the production of these products under controlled conditions.
SCIGENICS (INDIA) PRIVATE LIMITED
Plot H4,5,&6,3rd Cross Street,
Nehru Nagar, Perungudi,
Chennai- 600096, Tamil Nadu, India.
+91 9344212722
sales@scigenics.in
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